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KMID : 0363219950330040710
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Korean Journal of Dermatology
1995 Volume.33 No. 4 p.710 ~ p.716
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A Case of Unilateral Nevoid Tellangiectasia Associaed with canthosis Nigricans
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Abstract
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We report a case of unilateral nevoid telangiectasia associated with acanthosis nigricans in a 20-year old male patients. Unilateral nevoid telangiectasia may be congenital or acquired. The unilateral and dermatomal distribution suggests that
distribution of target vessels is fixed and that they are sensivity to estrogen. Estrogens are mainly produced by the ovaries, but they are also produced by peripheral aromatization of androgen. Because a major site of this conversion is adipose
tissue,
estrogen can increase in an obese person. Obesity also reverses the metabolism of estrogen and increases the serum insulin level. Therefore it seems that obesity in our patient induces the development of unilateral nevoid telangiectasia and
acanthosis
nigricans. (Kor J Dermatol 1995;33(4) : 710~716)
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